G蛋白偶联受体&G蛋白

CAS号：198481-32-2

品名：1-[[4-[2-(氮杂环庚烷-1-基)乙氧基]苯基]甲基]-2-(4-羟基苯基)-3-甲基-吲哚-5-醇1-[[4-[2-(azepan-1-yl)ethoxy]phenyl]methyl]-2-(4-hydroxyphenyl)-3-methylindol-5-ol

中文别名：巴多昔芬;

英文别名：TSE-424;bazedoxifene;Conbriza;Bazedoxifeno;

分子式：C30H34N2O3

分子量：470.603

精确质量：470.257

Psa：57.86

UNII号：Q16TT9C5BK

密度：1.19g/cm3

沸点：694.4ºC at 760 mmHg

闪点：373.8ºC

折射率：1.622

蒸汽压：6.33E-20mmHg at 25°C

简介：Bazedoxifeneisathirdgenerationselectiveestrogenreceptormodulator(SERM),developedbyPfizerfollowingthecompletionoftheirtakeoverofWyethPharmaceuticals.Inlate2013,PfizerreceivedapprovalforbazedoxifeneaspartofthecombinationdrugDUAVEEintheprevention(nottreatment)ofpostmenopausalosteoporosis.BazedoxfieneistheresultofanexclusiveresearchcollaborationbetweenWyethPharmaceuticalsandLigandPharmaceuticals.