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CAS:198481-32-2

 198481-32-2

198481-32-2

CAS号:198481-32-2

品名:1-[[4-[2-(氮杂环庚烷-1-基)乙氧基]苯基]甲基]-2-(4-羟基苯基)-3-甲基-吲哚-5-醇1-[[4-[2-(azepan-1-yl)ethoxy]phenyl]methyl]-2-(4-hydroxyphenyl)-3-methylindol-5-ol

中文别名:巴多昔芬;

英文别名:TSE-424;bazedoxifene;Conbriza;Bazedoxifeno;

分子式:C30H34N2O3

分子量:470.603

精确质量:470.257

Psa:57.86

UNII号:Q16TT9C5BK

密度:1.19g/cm3

沸点:694.4ºC at 760 mmHg

闪点:373.8ºC

折射率:1.622

蒸汽压:6.33E-20mmHg at 25°C

简介:Bazedoxifeneisathirdgenerationselectiveestrogenreceptormodulator(SERM),developedbyPfizerfollowingthecompletionoftheirtakeoverofWyethPharmaceuticals.Inlate2013,PfizerreceivedapprovalforbazedoxifeneaspartofthecombinationdrugDUAVEEintheprevention(nottreatment)ofpostmenopausalosteoporosis.BazedoxfieneistheresultofanexclusiveresearchcollaborationbetweenWyethPharmaceuticalsandLigandPharmaceuticals.

G蛋白偶联受体&G蛋白

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