CAS号:198481-32-2
品名:1-[[4-[2-(氮杂环庚烷-1-基)乙氧基]苯基]甲基]-2-(4-羟基苯基)-3-甲基-吲哚-5-醇1-[[4-[2-(azepan-1-yl)ethoxy]phenyl]methyl]-2-(4-hydroxyphenyl)-3-methylindol-5-ol
中文别名:巴多昔芬;
英文别名:TSE-424;bazedoxifene;Conbriza;Bazedoxifeno;
分子式:C30H34N2O3
分子量:470.603
精确质量:470.257
Psa:57.86
UNII号:Q16TT9C5BK
密度:1.19g/cm3
沸点:694.4ºC at 760 mmHg
闪点:373.8ºC
折射率:1.622
蒸汽压:6.33E-20mmHg at 25°C
简介:Bazedoxifeneisathirdgenerationselectiveestrogenreceptormodulator(SERM),developedbyPfizerfollowingthecompletionoftheirtakeoverofWyethPharmaceuticals.Inlate2013,PfizerreceivedapprovalforbazedoxifeneaspartofthecombinationdrugDUAVEEintheprevention(nottreatment)ofpostmenopausalosteoporosis.BazedoxfieneistheresultofanexclusiveresearchcollaborationbetweenWyethPharmaceuticalsandLigandPharmaceuticals.
G蛋白偶联受体&G蛋白