荧光探针，标记，颗粒和染色

CAS号：108964-32-5

品名：荧光钙探针Fura2-AMacetyloxymethyl2-[5-[bis[2-(acetyloxymethoxy)-2-oxoethyl]amino]-4-[2-[2-[bis[2-(acetyloxymethoxy)-2-oxoethyl]amino]-5-methylphenoxy]ethoxy]-1-benzofuran-2-yl]-1,3-oxazole-5-carboxylate

中文别名：AM荧光探针;钙离子荧光探针Fura2-AM;荧光钙探针Fura2-AM;FURA2-AMSPECIALPACKAGING;

英文别名：Fura2am;Fura-2pentakis(acetoxymethyl)ester;

分子式：C44H47N3O24

分子量：1001.85

精确质量：1001.25

Psa：327.11

BRN号：8183748

MDL号：MFCD00036976

PubChem号：24894734

密度：1.4g/cm3

沸点：975.9ºC at 760mmHg

闪点：544ºC

折射率：1.566

储存条件：-20ºC

蒸汽压：0mmHg at 25°C

WGK Germany：3

简介：Fura-2-acetoxymethylester,oftenabbreviatedFura-2AM,isamembrane-permeablederivativeoftheratiometriccalciumindicatorFura-2usedinbiochemistrytomeasurecellularcalciumconcentrationsbyfluorescence.Whenaddedtocells,Fura-2AMcrossescellmembranesandonceinsidethecell,theacetoxymethylgroupsareremovedbycellularesterases.Removaloftheacetoxymethylestersregenerates\"Fura-2\",thepentacarboxylatecalciumindicator.MeasurementofCa2+-inducedfluorescenceatboth340nmand380nmallowsforcalculationofcalciumconcentrationsbased340/380ratios.Theuseoftheratioautomaticallycancelsoutcertainvariablessuchaslocaldifferencesinfura-2concentrationorcellthicknessthatwouldotherwiseleadtoartifactswhenattemptingtoimagecalciumconcentrationsincells.