荧光探针,标记,颗粒和染色
CAS号:108964-32-5
品名:荧光钙探针Fura2-AMacetyloxymethyl2-[5-[bis[2-(acetyloxymethoxy)-2-oxoethyl]amino]-4-[2-[2-[bis[2-(acetyloxymethoxy)-2-oxoethyl]amino]-5-methylphenoxy]ethoxy]-1-benzofuran-2-yl]-1,3-oxazole-5-carboxylate
中文别名:AM荧光探针;钙离子荧光探针Fura2-AM;荧光钙探针Fura2-AM;FURA2-AMSPECIALPACKAGING;
英文别名:Fura2am;Fura-2pentakis(acetoxymethyl)ester;
分子式:C44H47N3O24
分子量:1001.85
精确质量:1001.25
Psa:327.11
BRN号:8183748
MDL号:MFCD00036976
PubChem号:24894734
密度:1.4g/cm3
沸点:975.9ºC at 760mmHg
闪点:544ºC
折射率:1.566
储存条件:-20ºC
蒸汽压:0mmHg at 25°C
WGK Germany:3
简介:Fura-2-acetoxymethylester,oftenabbreviatedFura-2AM,isamembrane-permeablederivativeoftheratiometriccalciumindicatorFura-2usedinbiochemistrytomeasurecellularcalciumconcentrationsbyfluorescence.Whenaddedtocells,Fura-2AMcrossescellmembranesandonceinsidethecell,theacetoxymethylgroupsareremovedbycellularesterases.Removaloftheacetoxymethylestersregenerates\"Fura-2\",thepentacarboxylatecalciumindicator.MeasurementofCa2+-inducedfluorescenceatboth340nmand380nmallowsforcalculationofcalciumconcentrationsbased340/380ratios.Theuseoftheratioautomaticallycancelsoutcertainvariablessuchaslocaldifferencesinfura-2concentrationorcellthicknessthatwouldotherwiseleadtoartifactswhenattemptingtoimagecalciumconcentrationsincells.