膜转运/离子通道

CAS号：122647-32-9

品名：富马酸伊布利特IbutilideHemifumarate

中文别名：伊布利特;N-[4-[4-(乙基庚基胺)-1-羟基丁基]苯基]甲磺酰胺富马酸盐;伊布利特半富马酸盐;

英文别名：Ibutilidehemifumaratesalt;Ibutilidefumarate;IbutilideFumarate;

分子式：C44H76N4O10S2

分子量：885.225

精确质量：884.5

Psa：230.64

UNII号：9L5X4M5L6I

密度：

沸点：522.4ºC at 760 mmHg

闪点：269.7ºC

蒸汽压：9.71E-12mmHg at 25°C

信号词：Warning

危险标志：GHS07

危险性描述：H302

简介：IbutilideisaClassIIIantiarrhythmicagentthatisindicatedforacutecardioconversionofatrialfibrillationandatrialflutterofarecentonsettosinusrhythm.Itexertsitsantiarrhythmiceffectbyinductionofslowinwardsodiumcurrent,whichprolongsactionpotentialandrefractoryperiod(physiology)ofmyocardialcells.BecauseofitsClassIIIantiarrhythmicactivity,thereshouldnotbeconcomitantadministrationofClassIaandClassIIIagents.