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CAS:122647-32-9
122647-32-9
CAS号：122647-32-9
品名：富马酸伊布利特IbutilideHemifumarate
中文别名：伊布利特;N-[4-[4-(乙基庚基胺)-1-羟基丁基]苯基]甲磺酰胺富马酸盐;伊布利特半富马酸盐;
英文别名：Ibutilidehemifumaratesalt;Ibutilidefumarate;IbutilideFumarate;
分子式：C44H76N4O10S2
分子量：885.225
精确质量：884.5
Psa：230.64
UNII号：9L5X4M5L6I
密度：
沸点：522.4ºC at 760 mmHg
闪点：269.7ºC
蒸汽压：9.71E-12mmHg at 25°C
信号词：Warning
危险标志：GHS07
危险性描述：H302
简介：IbutilideisaClassIIIantiarrhythmicagentthatisindicatedforacutecardioconversionofatrialfibrillationandatrialflutterofarecentonsettosinusrhythm.Itexertsitsantiarrhythmiceffectbyinductionofslowinwardsodiumcurrent,whichprolongsactionpotentialandrefractoryperiod(physiology)ofmyocardialcells.BecauseofitsClassIIIantiarrhythmicactivity,thereshouldnotbeconcomitantadministrationofClassIaandClassIIIagents.
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