其他分子
CAS号:129497-78-5
品名:维替泊芬Verteporfin
中文别名:微替泊芬;
英文别名:Verteprofin;Verteporphin;trans-3,4-Dicarboxy-4,4a-dihydro-4a,8,14,19-tetramethyl-18-vinyl-23H,25H-benzo(b)porphine-9,13-dipropionicacid3,4,9-trimethylester;Visudyne;VERTEPORFIN(200MG);
分子式:C82H84N8O16
分子量:1437.59
精确质量:1436.6
Psa:337.48
UNII号:0X9PA28K43
外观与性状:暗绿色至黑色固体
密度:
简介:Verteporfin(tradenameVisudyne),abenzoporphyrinderivative,isamedicationusedasaphotosensitizerforphotodynamictherapytoeliminatetheabnormalbloodvesselsintheeyeassociatedwithconditionssuchasthewetformofmaculardegeneration.Verteporfinaccumulatesintheseabnormalbloodvesselsand,whenstimulatedbynonthermalredlightwithawavelengthof689nminthepresenceofoxygen,produceshighlyreactiveshort-livedsingletoxygenandotherreactiveoxygenradicals,resultinginlocaldamagetotheendotheliumandblockageofthevessels.