4-Chloro-N-imidazolidin-2-yl... 4-Chloro-N-imidazolidin-2-yl... 1g

CAS号：75438-57-2

品名：莫索尼啶Moxonidine

中文别名：莫索尼定,不带盐酸;4-氯-N-(4,5-二氢-1H-咪唑-2-基)-6-甲氧基-2-甲基-5-嘧啶胺;莫索尼定;

英文别名：Lomox;Norcynt;[14C]-Moxonidine;4-chloro-5-[(4,5-dihydro-1H-imidazol-2-yl)-amino]-6-methoxy-2-methylpyrimidine;Moxonidinum[Latin];4-chloro-5-(imidazoline-2-ylamino)-6-methoxy-2-methylpyrimidine;BE5895;Moxonidine;Cynt;MOXONIDINE;Nucynt;Physiotens;4-chloro-N-(4,5-dihydro-1H-imidazol-2-yl)-6-methoxy-2-methyl-5-pyrimidinamine;4-chloro-N-(4,5-dihydro-1H9imidazol-yl)-6-methoxy-2-methyl-5-pyrimidinamine;Normoxocin;[3H]-Moxonidine;

分子式：C9H12ClN5O

分子量：241.677

精确质量：241.073

Psa：71.43

RTECS号：UV6260290

MDL号：MFCD22689455

外观与性状：晶体

密度：1.52 g/cm3 (20ºC)

沸点：364.7ºC at 760 mmHg

熔点：40-43°C(lit.)

闪点：&>230°F

折射率：1.68

储存条件：Store in original container in a cool dark place.

WGK Germany：3

简介：Moxonidine(INN)isanew-generationcentrallyactingantihypertensivedruglicensedforthetreatmentofmildtomoderateessentialhypertension.Itmayhavearolewhenthiazides,beta-blockers,ACEinhibitorsandcalciumchannelblockersarenotappropriateorhavefailedtocontrolbloodpressure.Inaddition,itdemonstratesfavourableeffectsonparametersoftheinsulinresistancesyndrome,apparentlyindependentofbloodpressurereduction.ItismanufacturedbySolvayPharmaceuticalsunderthebrandnamePhysiotens.

用途：通过刺激中枢突触前α2-受体而起效。其降压效果和钙拮抗剂硝苯地平和ACE抑制剂卡托普利相似。用于原发性高血压。