其他分子
CAS号：94497-51-5
品名：他米巴罗汀tamibarotene
中文别名：TAMIBAROTENE,AM80,AM-80,AM80;4-[(5,5,8,8-四甲基-6,7-二氢萘-2-基)氨基甲酰]苯甲酸;
英文别名：4-[(5,5,8,8-tetramethyl-6,7-dihydronaphthalen-2-yl)carbamoyl]benzoicacid;4-((5,5,8,8-Tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)carbamoyl)benzoicacid;
分子式：C22H25NO3
分子量：351.439
精确质量：351.183
Psa：66.4
MDL号：MFCD00866188
外观与性状：结晶固体
密度：1.154g/cm3
沸点：449.6ºC at 760mmHg
熔点：231-232ºC
闪点：225.7ºC
折射率：1.593
海关编码：2924299090
简介：Tamibarotene(brandname:Amnolake),alsocalledretinobenzoicacid,isorallyactive,syntheticretinoid,developedtoovercomeall-transretinoicacid(ATRA)resistance,withpotentialantineoplasticactivityagainstacutepromyelocyticleukaemia(APL).ItiscurrentlymarketedonlyinJapanandearlytrialshavedemonstratedthatittendstobebettertoleratedthanATRA.IthasalsobeeninvestigatedasapossibletreatmentforAlzheimer'sdisease,multiplemyelomaandCrohn'sdisease.
