CAS:908112-43-6
908112-43-6
CAS号：908112-43-6
品名：SNX2112;2-[(反式-4-羟基环己基)氨基]-4-[4,5,6,7-四氢-6,6-二甲基-4-氧代-3-(三氟甲基)-1H-吲唑-1-基]苯甲酰胺PF-04928473
中文别名：SNX2112;2-[(反式-4-羟基环己基)氨基]-4-[4,5,6,7-四氢-6,6-二甲基-4-氧代-3-(三氟甲基)-1H-吲唑-1-基]苯甲酰胺
英文别名：4-[6,6-dimethyl-4-oxo-3-(trifluoromethyl)-5,7-dihydroindazol-1-yl]-2-[(4-hydroxycyclohexyl)amino]benzamide;SNX-2112;4-(6,6-dimethyl-4-oxo-3-(trifluoromethyl)-4,5,6,7-tetrahydro-1H-indazol-1-yl)-2-((4-hydroxycyclohexyl)amino)benzamide;
分子式：C23H27F3N4O3
分子量：464.481
精确质量：464.204
Psa：110.24
MDL号：MFCD16038907
密度：1.5±0.1g/cm3
沸点：619.8±55.0°Cat760mmHg
熔点：265-266℃
闪点：328.6±31.5°C
折射率：1.638
储存条件：-20℃
蒸汽压：0.0±1.9mmHgat25°C
简介：SNX-2112isaselectiveheatshockprotein90(Hsp90)inhibitorwhichcanexertapotentanticanceractivity.StudiesdemonstatesthatSNX-2112canexhibitapotentanticanceractivityagainstB16melanomacellsbothinvitroandinvivo,byinhibitingcellproliferationandinducingcellcyclearrestandapoptosisinamechanismdependentonthedegredationofHsp90clientproteins.
细胞骨架信号
