CAS:149-87-1
149-87-1
CAS号：149-87-1
品名：DL-焦谷氨酸5-oxoproline
中文别名：吡咯烷酮羧酸;DL-谷氨酸-Y-内酰胺;DL-2-吡咯烷酮-5-羧酸;5-氧代吡咯烷-2-羧酸;2-吡咯烷酮-5-甲酸;(±)-2-吡咯烷酮-5-羧酸;DL-焦性胶氨酸;2-吡咯烷酮-5-羧酸;
英文别名：DL-Pyroglutamicacid;5-Oxopyrrolidine-2-carboxylicAcid;D,l-2-Pyrrolidone-5-CarboxylicAcid;2-Pyrrolidone-5-carboxylicacid;DL-2-Pyrrolidone-5-carboxylicacid;H-DL-Pyr-OH;DL-GlutamicAcidLactam;DL-PyroglutamicAcid;
分子式：C5H7NO3
分子量：129.114
精确质量：129.043
Psa：66.4
BRN号：82131
EINECS号：205-748-3
MDL号：MFCD00064322
PubChem号：24857617
外观与性状：白色粉末
密度：1.38 g/cm3
沸点：453.1ºC at 760 mmHg
熔点：180-185ºC
闪点：227.8ºC
折射率：1.511
稳定性：Stable under normal temperatures and pressures.
储存条件：Keep container closed when not in use. Store in a cool, dry, well-ventilated area away from incompatible substances. Keep containers tightly closed.
蒸汽压：1.79E-09mmHg at 25°C
安全说明：S26-S37/39
危险类别码：R36/37/38
海关编码：29337900
危险品标志：Xi
信号词：Warning
危险性防范说明：P261; P305 + P351 + P338
危险标志：GHS07
危险性描述：H302; H315; H319; H335
简介：Pyroglutamicacid(alsoknownasPCA,5-oxoproline,pidolicacid,orpyroglutamateforitsbasicform)isanuncommonandlittlestudiedaminoacidderivativeinwhichthefreeaminogroupofglutamicacidorglutaminecyclizestoformalactam.Itisametaboliteintheglutathionecyclethatisconvertedtoglutamateby5-oxoprolinase.Pyroglutamateisfoundinmanyproteinsincludingbacteriorhodopsin.N-terminalglutamicacidandglutamineresiduescanspontaneouslycyclizetobecomepyroglutamate.ThisisoneofseveralformsofblockedN-terminalswhichpresentaproblemforN-terminalsequencingusingEdmanchemistry,whichrequiresafreeprimaryaminogroupnotpresentinpyroglutamicacid.TheenzymepyroglutamateaminopeptidasecanrestoreafreeN-terminusbycleavingoffthepyroglutamateresidue.
用途：医药中间体；化妆品原料；用作生化试剂。
氨基酸
