CAS:718630-59-2
718630-59-2
CAS号：718630-59-2
品名：PHA-793887;3-甲基-N-[1,4,5,6-四氢-6,6-二甲基-5-[(1-甲基-4-哌啶基)甲酰基]吡咯并[3,4-c]吡唑-3-基]丁酰胺N-[6,6-dimethyl-5-(1-methylpiperidine-4-carbonyl)-1,4-dihydropyrrolo[3,4-c]pyrazol-3-yl]-3-methylbutanamide
中文别名：PHA-793887;3-甲基-N-[1,4,5,6-四氢-6,6-二甲基-5-[(1-甲基-4-哌啶基)甲酰基]吡咯并[3,4-c]吡唑-3-基]丁酰胺
英文别名：N-(6,6-Dimethyl-5-(1-methylpiperidine-4-carbonyl)-1,4,5,6-tetrahydropyrrolo(3,4-C)pyrazol-3-yl)-3-methylbutanamide;3-Methyl-N-[1,4,5,6-tetrahydro-6,6-dimethyl-5-[(1-methyl-4-piperidinyl)carbonyl]pyrrolo[3,4-c]pyrazol-3-yl]butanamide;
分子式：C19H31N5O2
分子量：361.482
精确质量：361.248
Psa：84.82
密度：1.176 g/cm3
沸点：596.226ºC at 760 mmHg
闪点：314.386ºC
简介：PHA-793887isapotentCDK(cyclin-dependentkinase)inhibitor.RecentstudiesshowsthatPHA-793887haspromisingtherapeuticactivityagainstacuteleukemiasinvitroandinvivo.PHA-793887wasusedtosuccessfullymodulateE2Ftranscriptionalfactor-dependentcellcycle,DNAreplication,mitosisandapoptosisrelatedgeneinbothtumorsandskinbiopsyfrompatientswithsolidtumors.
细胞周期
