CAS:87-11-6
87-11-6
CAS号：87-11-6
品名：硫藤黄素N-(4-methyl-5-oxodithiolo[4,3-b]pyrrol-6-yl)acetamide
中文别名：硫藤黄菌素;
英文别名：Thiolutin;3-Acetamido-5-methylpyrrolin-4-one(4,3-d)-1,2-dithiole;Acetopyrrothin;6-acetylamino-4-methyl-4H-[1,2]dithiolo[4,3-b]pyrrol-5-one;Acetopyrrothine;6-Acetamido-4-methyl-1,2-dithiolo&<4,3-b&>pyrrol-5(4H)-on;N-(4-Methyl-5-oxo-4,5-dihydro-[1,2]dithiolo[4,3-b]pyrrol-6-yl)-acetamid;N-(4-methyl-5-oxo-4,5-dihydro-[1,2]dithiolo[4,3-b]pyrrol-6-yl)-acetamide;6-(Acetylamino)-4-methyl-1,2-dithiolo(4,3-b)pyrrol-5(4H)-one;6-Acetamido-4-methyl-1,2-dithiolo(4,3-b)pyrrol-5(4H)-one;
分子式：C8H8N2O2S2
分子量：228.291
精确质量：228.003
Psa：107.58
MDL号：MFCD07370147
密度：1.55g/cm3
沸点：478.6ºC at 760 mmHg
闪点：243.3ºC
折射率：1.72
储存条件：库房通风低温干燥
危险类别码：R28
海关编码：2933990090
危险品运输编码：UN 2811 6.1/PG 2
危险品标志：T+
简介：Thiolutinisasulfur-containingantibiotic,whichisapotentinhibitorofbacterialandyeastRNApolymerases.ItwasfoundtoinhibitinvitroRNAsynthesisdirectedbyallthreeyeastRNApolymerases(I,II,andIII).ThiolutinisalsoaninhibitorofmannanandglucanformationinSaccharomycescerevisiaeandusedfortheanalysisofmRNAstability.Studieshaveshownthatthiolutininhibitsadhesionofhumanumbilicalveinendothelialcells(HUVECs)tovitronectinandthussuppressestumorcell-inducedangiogenesisinvivo.
抗生素
