神经信号

CAS号：607742-69-8

品名：3-苯磺酰基-8-(哌嗪-1-基)喹啉3-(benzenesulfonyl)-8-piperazin-1-ylquinoline

中文别名：渥曼青霉素;

英文别名：Quinoline,3-(phenylsulfonyl)-8-(1-piperazinyl);3-(phenylsulfonyl)-8-(piperazin-1-yl)quinoline;

分子式：C19H19N3O2S

分子量：353.438

精确质量：353.12

Psa：70.68

UNII号：2IOB2M82HY

密度：1.3±0.1g/cm3

沸点：608.3±45.0°Cat760mmHg

闪点：321.7±28.7°C

折射率：1.649

储存条件：-20℃

蒸汽压：0.0±1.7mmHgat25°C

简介：Intepirdine(INN;developmentalcodesSB-742457,RVT-101)isaselective5-HT6receptorantagonistwithpotentialcognition,memory,andlearning-enhancingeffects.ItwasunderdevelopmentbyGlaxoSmithKlineforthetreatmentofAlzheimer'sdiseaseanddemonstratedsomepreliminaryefficacyinphaseIIclinicaltrials;however,GSKchosenottocontinuedevelopmentandsoldtherightstoAxovantSciencesinDecember2014.