CAS号:539-15-1
品名:大麦芽碱hordenine
中文别名:4-羟基-N,N-二甲基苯乙胺;4-(2-二甲基氨基乙基)苯酚;麦芽碱;大麦碱;安哈林;對羥-N,N-二甲苯乙胺;氮位N,N-二甲基对羟基苯乙胺;4-[2-(二甲基氨基)乙基]苯酚;
英文别名:4-[2-(Dimethylamino)ethyl]phenol;Cactine;Anhaline;N,N-dimethyltyramine;Hordenin;Phenol,4-[2-(dimethylamino)ethyl]-;Hordetin;p-[2-(dimethylamino)ethyl]phenol;Hordenine;4-(2-(Dimethylamino)ethyl)phenol;Ordenina;Eremursine;2-(4-Hydroxyphenyl)-N,N-dimethylethylamine(4-(2-Dimethylaminoethyl)phenol;Anhalin;4-Hydroxy-N,N-dimethylphenethylamine;4-[2-(dimethylamino)ethyl]phenol;Anhalin-d6;N,N-dimethyl-2-(4-hydroxyphenyl)ethylamine;Ordenine;
分子式:C10H15NO
分子量:165.232
精确质量:165.115
Psa:23.47
EINECS号:208-710-4
密度:1.026g/cm3
沸点:270.2ºC at 760 mmHg
闪点:123.5ºC
折射率:1.542
海关编码:2922199090
简介:Hordenine(N,N-dimethyltyramine)isanalkaloidofthephenethylamineclassthatoccursnaturallyinavarietyofplants,takingitsnamefromoneofthemostcommon,barley(Hordeumspecies).Chemically,hordenineistheN-methylderivativeofN-methyltyramine,andtheN,N-dimethylderivativeofthewell-knownbiogenicaminetyramine,fromwhichitisbiosyntheticallyderivedandwithwhichitsharessomepharmacologicalproperties(seebelow).Currently,hordenineiswidelysoldasaningredientofnutritionalsupplements,withtheclaimsthatitisastimulantofthecentralnervoussystem,andhastheabilitytopromoteweightlossbyenhancingmetabolism.Inexperimentalanimals,givensufficientlylargedosesparenterally(i.e.byinjection),hordeninedoesproduceanincreaseinbloodpressure,aswellasotherdisturbancesofthecardio-vascular,respiratoryandnervoussystems.Theseeffectsaregenerallynotreproducedbyoraladministrationofthedrugintestanimals,andtherearevirtuallynoscientificreportsoftheeffectsofhordenineinhumanbeings.Moredetaileddiscussionsofhordeninepharmacologyandtoxicologyaregivenbelowthissection.