代谢
CAS号：154229-19-3
品名：阿比特龙abiraterone
中文别名：坦度酮罗;17-(3-吡啶基)雄甾-5,16-二烯-3beta-醇;
英文别名：Abiraterone;(3beta)-17-(3-pyridinyl)-androsta-5,16-dien-3-ol;
分子式：C24H31NO
分子量：349.509
精确质量：349.241
Psa：33.12
MDL号：MFCD00924100
密度：1.14g/cm3
沸点：500.2ºC at 760mmHg
闪点：256.3ºC
折射率：1.605
蒸汽压：7.99E-11mmHg at 25°C
海关编码：2933399090
简介：Abirateroneacetate(INN,USAN,BAN,JAN)(brandnamesZytiga,Abiratas,Abretone,Abirapro)isasteroidalantiandrogen,specificallyanandrogensynthesisinhibitor,usedincombinationwithprednisoneinmetastaticcastration-resistantprostatecancer(previouslycalledhormone-resistantorhormone-refractoryprostatecancer)–i.e.,prostatecancernotrespondingtoandrogendeprivationortreatmentwithandrogenreceptorantagonists.Itisaprodrugtotheactiveagentabiraterone,andismarketedbyJanssenBiotechunderthetradenameZytiga.Inaddition,IntasPharmaceuticalsmarketsthedrugunderthetradenameAbiratas,CadilaPharmaceuticalsmarketsthedrugasAbretone,andGlenmarkPharmaceuticalsasAbirapro.
用途：雄激素拮抗药。
