普乐沙福 Plerixafo 1ml

CAS号：110078-46-1

品名：普乐沙福Plerixafor

中文别名：MOZOBILPLERIXAFOR;

英文别名：Mozobil;Unii-S915p5499n;1,4-Bis((1,4,8,11-tetraazacyclotetradecan-1-yl)methyl)benzene;Sdzsid791;

分子式：C28H54N8

分子量：502.782

精确质量：502.447

Psa：78.66

MDL号：MFCD05662218

密度：0.962

沸点：657.5ºC at 760 mmHg

闪点：361.8ºC

蒸汽压：1.06E-34mmHg at 25°C

海关编码：2933990090

简介：Plerixaforisahematopoieticstemcell(HSC)mobilizerthatinhibitstheCXCR4chemokinereceptorandblocksbindingofitsligand,stromalcell-derivedfactor-1-α(SDF-1-α).ThisagentwasapprovedonDec.15,2008,astreatmentincombinationwithgranulocyte-colonystimulatingfactor(G-CSF)tomobilizeHSCstotheperipheralbloodforcollectionandsubsequentautologoustransplantationinpatientswithnon-Hodgkin'slymphoma(NHL)andmultiplemyeloma(MM).