细胞骨架信号
CAS号：152044-53-6
品名：西洛他唑(1R,5S,6S,7R,10S,14S,16S)-6,10-dihydroxy-5,7,9,9-tetramethyl-14-[(E)-1-(2-methyl-1,3-thiazol-4-yl)prop-1-en-2-yl]-13,17-dioxabicyclo[14.1.0]heptadecane-8,12-dione
中文别名：埃博霉素A;
英文别名：EpoA;EpothiloneA;Epothilones;EpothilonA;epithiloneA;
分子式：C26H39NO6S
分子量：493.656
精确质量：493.25
Psa：137.49
密度：1.143g/cm3
沸点：683.3ºC at 760 mmHg
熔点：95ºC
闪点：367.1ºC
折射率：1.531
蒸汽压：1.31E-19mmHg at 25°C
简介：Theepothilonesareanovelclassofantineoplasticagentspossessingantitubulinactivity.EpothiloneA,BisolatedfromSorangiumcellulosumwasassociatedwithcellcyclearrestatG2/Mtransitionandapoptosisthatwasresistedwithoverexpressionofβ-tubulinandP-glycoproteininhumanbladdercarcinomacell.
