神经信号
CAS号：607742-69-8
品名：3-苯磺酰基-8-(哌嗪-1-基)喹啉3-(benzenesulfonyl)-8-piperazin-1-ylquinoline
中文别名：渥曼青霉素;
英文别名：Quinoline,3-(phenylsulfonyl)-8-(1-piperazinyl);3-(phenylsulfonyl)-8-(piperazin-1-yl)quinoline;
分子式：C19H19N3O2S
分子量：353.438
精确质量：353.12
Psa：70.68
UNII号：2IOB2M82HY
密度：1.3±0.1g/cm3
沸点：608.3±45.0°Cat760mmHg
闪点：321.7±28.7°C
折射率：1.649
储存条件：-20℃
蒸汽压：0.0±1.7mmHgat25°C
简介：Intepirdine(INN;developmentalcodesSB-742457,RVT-101)isaselective5-HT6receptorantagonistwithpotentialcognition,memory,andlearning-enhancingeffects.ItwasunderdevelopmentbyGlaxoSmithKlineforthetreatmentofAlzheimer'sdiseaseanddemonstratedsomepreliminaryefficacyinphaseIIclinicaltrials;however,GSKchosenottocontinuedevelopmentandsoldtherightstoAxovantSciencesinDecember2014.
