多肽
CAS号：86933-75-7
品名：神经激肽BNeurokininB(human,porcine)
中文别名：β-Neurokinin;
英文别名：NEUROMEDINK;NEUROKININB;NEUROKININK;NeurokininBNKB;NKB;DMHDFFVGLM-NH2;
分子式：C55H79N13O14S2
分子量：1210.42
精确质量：1209.53
Psa：484.89
MDL号：MFCD00133665
PubChem号：24897694
密度：1.313 g/cm3
沸点：1646ºC at 760 mmHg
闪点：949.3ºC
折射率：1.591
储存条件：-20ºC
简介：NeurokininB(NKB)belongsinthefamilyoftachykininpeptides.NeurokininBisimplicatedinavarietyofhumanfunctionsandpathwayssuchasthesecretionofgonadotropin-releasinghormone.Additionally,NKBisassociatedwithpregnancyinfemalesandmaturationinyoungadults.ReproductivefunctionishighlydependentonlevelsofbothneurokininBandalsotheG-proteincoupledreceptorligandkisspeptin.ThefirstNKBstudiesdoneattemptedtoresolvewhyhighlevelsofthepeptidemaybeimplicatedinpre-eclampsiaduringpregnancy.NKB,kisspeptin,anddynorphintogetherarefoundinthearcuatenucleus(ARC)knownastheKNDysubpopulation.ThissubpopulationistargetedbyalargenumberofsteroidhormonesandworkstoformanetworkthatfeedsbacktoGnRHpulsegenerator.
