蛋白酶
CAS号:1194044-20-6
品名:(4S)-4-[2,4-二氟-5-(5-嘧啶)苯基]-5,6-二氢-4-甲基-4H-1,3-噻嗪-2-胺(S)-4-(2,4-Difluoro-5-(pyrimidin-5-yl)phenyl)-4-methyl-5,6-dihydro-4H-1,3-thiazin-2-amine
中文别名:(4S)-4-[2,4-二氟-5-(5-嘧啶基)苯基]-5,6-二氢-4-甲基-4H-1,3-噻嗪-2-胺;
英文别名:(4S)-4-(2,4-difluoro-5-pyrimidin-5-ylphenyl)-4-methyl-5,6-dihydro-1,3-thiazin-2-amine;
分子式:C15H14F2N4S
分子量:320.36
精确质量:320.091
Psa:89.46
MDL号:MFCD18074525
密度:1.4±0.1g/cm3
沸点:486.5±55.0°Cat760mmHg
闪点:248.0±31.5°C
折射率:1.662
储存条件:室温,干燥,密封
蒸汽压:0.0±1.2mmHgat25°C
海关编码:2934999090
简介:LY281137isacompoundcapableofthedecreaseinβ-amyloidpeptide(Aβ)associatedwiththecleavageofamyloidprecursorprotein(APP)byβ-secretase(BACE)andγ-secretase.Thisdecreaseisimportantasitshypothesizedthatthebuildupof(Aβ)inthebrainisaprimarycauseofneurodegenerationandAlzheimer’sprogression.