血管再生
CAS号:446-72-0
品名:染料木素Genistein
中文别名:染料木黄酮;金雀异黄素;4',5,7-三羟基异黄酮;5,7-二羟基-3-(4-羟苯基)-4H-1-苯并吡喃-4-酮;三羟基异黄酮;金雀异黄酮;
英文别名:5,7,4'-trihydroxyisoflavone;5,7-Dihydroxy-3-(4-hydroxyphenyl)-4H-chromen-4-one;5,7-Dihydroxy-3-(4-hydroxyphenyl)-4H-1-benzopyran-4-one;4',5,7-Trihydroxyisoflavone;Genistein;GeniVida;BonisteinNPI031L;prunetol;sophoricol;4H-1-Benzopyran-4-one,5,7-dihydroxy-3-(4-hydroxyphenyl)-;genisteol;GLYCITEN;
分子式:C15H10O5
分子量:270.237
精确质量:270.053
Psa:90.9
RTECS号:NR2392000
MDL号:MFCD00016952
外观与性状:黄色结晶固体
密度:1.548 g/cm3
沸点:555.5ºC at 760 mmHg
熔点:297-298 °C
闪点:217.1ºC
折射率:1.732
储存条件:-20ºC
蒸汽压:6E-13mmHg at 25°C
安全说明:S26-S24/25-S22
危险类别码:R36/38
WGK Germany:3
海关编码:2932999099
危险品标志:Xi
信号词:Warning
危险标志:GHS07
危险性描述:H302
简介:Exhibitsspecificinhibitoryactivityagainsttyrosinekinases,includingautophosphorylationofepidermalgrowthfactorreceptorkinase(IC50-2.6uM).AlsoinhibitsotherproteinkinasesthroughcompetitiveinhibitionofATP.Inhibitstumorcellproliferationandinducestumorcelldifferentiation.Producescell-cyclearrestandapoptosisinJuratT-leukemiacells.However,itpreventsanti-CD3monoclonalantibody-inducedthymicapoptosis.GenisteinalsoinhibitstopoisomeraseIIactivityinvitro.GenisteinhasalsobeenshowntoinhibittheactionofGABAonrecombinantGABAAreceptors2.uv(max)ethanol:262.5nm(e=138).moderatelysol.inhotalcohol
用途:有抗肿瘤、降血脂作用,还有雌激素样作用。