Olcegepant,CGRP-1受体拮抗剂 Olcegepant 25mg

CAS号：204697-65-4

品名：Olcegepant;N-[2-[5-氨基-1(S)-[4-(4-吡啶基)哌嗪-1-甲酰基]戊基氨基]-1(R)-(3,5-二溴-4-羟基苄基)-2-氧代乙基]-4-(2-氧代-1,2,3,4-四氢喹唑啉-3-基)哌啶-1-甲酰胺N-[(2R)-1-[[(2S)-6-amino-1-oxo-1-(4-pyridin-4-ylpiperazin-1-yl)hexan-2-yl]amino]-3-(3,5-dibromo-4-hydroxyphenyl)-1-oxopropan-2-yl]-4-(2-oxo-1,4-dihydroquinazolin-3-yl)piperidine-1-carboxamide

中文别名：Olcegepant;N-[2-[5-氨基-1(S)-[4-(4-吡啶基)哌嗪-1-甲酰基]戊基氨基]-1(R)-(3,5-二溴-4-羟基苄基)-2-氧代乙基]-4-(2-氧代-1,2,3,4-四氢喹唑啉-3-基)哌啶-1-甲酰胺

英文别名：Olcegepant[INN];BIBN4096;BIBN4096BS;Olcegepant;

分子式：C38H47Br2N9O5

分子量：869.645

精确质量：867.207

Psa：186.94

密度：

蒸汽压：0mmHg at 25°C

简介：Olcegepantisapotentandselectivecalcitoningene-relatedpeptide(CGRP)receptorantagonist.OlcegepantdisplayshighaffinityforhumanCGRPreceptorsandexhibitsnosignificantaffinityfor75otherreceptors.Olcegepantmayabeviableoptionforthetreatmentofacutemigraines.