2,3-双(4-羟基苯基)丙腈 2,3-bis(4-hydroxyphenyl)prop... 5mg

CAS号：1428-67-7

品名：2,3-双(4-羟苯基)丙腈2,3-bis(4-hydroxyphenyl)propionitrile

中文别名：2,3-双(4-羟苯基)丙腈

英文别名：2,3-bis(4-hydroxyphenyl)propanenitrile;2,3-Bis(4-hydroxyphenyl)propionitrile;DPNDiarylpropionitrileSC-4473;

分子式：C15H13NO2

分子量：239.269

精确质量：239.095

Psa：64.25

外观与性状：灰白色固体

密度：1.256 g/cm3

沸点：449.4ºC at 760 mmHg

闪点：225.6ºC

折射率：1.639

蒸汽压：1.08E-08mmHg at 25°C

信号词：Warning

危险性防范说明：P273; P305 + P351 + P338

危险标志：GHS07, GHS09

危险性描述：H319; H400

简介：Diarylpropionitrile(DPN),alsoknownas2,3-bis(p-hydroxyphenyl)propionitrile(2,3-BHPPN),isasynthetic,non-steroidal,andhighlyselectiveagonistofERβ(IC50=15nM)thatisusedwidelyinscientificresearchtostudythefunctionofthisreceptor.Itis70-foldmoreselectiveforERβoverERα,andhas100-foldloweraffinityforGPER(GPR30)relativetoestradiol.DPNproducesantidepressant-andanxiolytic-likeeffectsinanimalsviaactivationoftheendogenousoxytocinsystem.