神经信号
CAS号：132810-10-7
品名：布南色林Blonanserin
中文别名：布南瑟林;2-(4-乙基-1-哌嗪基)-4-(4-氟苯基)-5,6,7,8,9,10-六氢环辛[b]吡啶;布兰色林;
英文别名：2-(4-Ethyl-1-piperazinyl)-4-(4-fluorophenyl)-5,6,7,8,9,10-hexahydrocycloocta[b]pyridine;2-(4-ethylpiperazin-1-yl)-4-(4-fluorophenyl)-5,6,7,8,9,10-hexahydrocycloocta[b]pyridine;
分子式：C23H30FN3
分子量：367.503
精确质量：367.242
Psa：19.37
UNII号：AQ316B4F8C
密度：1.095 g/cm3
沸点：540.8ºC at 760mmHg
闪点：280.9ºC
折射率：1.557
蒸汽压：9.21E-12mmHg at 25°C
简介：Blonanserin(Lonasen)isarelativelynewatypicalantipsychotic(approvedbyPMDAinJanuary2008)commercializedbyDainipponSumitomoPharmainJapanandKoreaforthetreatmentofschizophrenia.Relativetomanyotherantipsychotics,blonanserinhasanimprovedtolerabilityprofile,lackingsideeffectssuchasextrapyramidalsymptoms,excessivesedation,orhypotension.Aswithmanysecond-generation(atypical)antipsychoticsitissignificantlymoreefficaciousinthetreatmentofthenegativesymptomsofschizophreniacomparedtofirst-generation(typical)antipsychoticssuchashaloperidol.
用途：精神分裂症治疗药
