钙荧光指示剂-1 Indo-1,pentapotassiumsalt,... 1MG

CAS号：96314-96-4

品名：钙荧光指示剂-1Indo-1dye

中文别名：INDO1;

英文别名：INDO-1,PentapotassiumSalt;2-[4-[bis(carboxymethyl)amino]-3-[2-[2-[bis(carboxymethyl)amino]-5-methylphenoxy]ethoxy]phenyl]-1H-indole-6-carboxylicacid;Indo1;

分子式：C32H31N3O12

分子量：649.601

精确质量：649.191

Psa：227.23

密度：1.527g/cm3

沸点：1016.3ºC at 760mmHg

折射率：1.707

储存条件：-20ºC

安全说明：S22-S24/25

简介：Indo-1isapopularcalciumindicatorsimilartoFura-2.IncontrasttoFura-2,Indo-1hasadualemissionspeak.Themainemissionpeakincalcium-freesolutionis475nmwhileinthepresenceofcalciumtheemissionisshiftedto400nm.Itiswidelyusedinflowcytometry.Thepentapotassiumsaltiscommerciallyavailableandpreferredtothefreeacidbecauseofitshighersolubilityinwater.WhileIndo-1isnotcellpermeablethepentaacetoxymethylesterIndo-1AMentersthecellwhereitiscleavedbyintracellularesterasestoIndo-1.ThesynthesisandpropertiesofIndo-1werepresentedin1985bythegroupofRogerYTsien.