阿伐那非 Avanafil,99% 5G

CAS号：330784-47-9

品名：阿伐那非avanafil

中文别名：4-[(3-氯-4-甲氧基苄基)氨基]-2-[2-(羟甲基)-1-吡咯烷基]-N-(2-嘧啶基甲基)-5-嘧啶甲磺酰胺;

英文别名：Avanafil;

分子式：C23H26ClN7O3

分子量：483.951

精确质量：483.179

Psa：125.39

MDL号：MFCD11977961

外观与性状：白色固体

密度：1.372g/cm3

熔点：150-152ºC

折射率：1.651

海关编码：2933990090

简介：AvanafilisaPDE5inhibitorapprovedforerectiledysfunctionbytheFDAonApril27,2012andbyEMAonJune21,2013.AvanafilisknownbythetrademarknamesStendraandSpedraandwasdevelopedbyVivusInc.InJuly2013VivusannouncedpartnershipwithMenariniGroup,whichwillcommercialiseandpromoteSpedrainover40EuropeancountriesplusAustraliaandNewZealand.Avanafilactsbyinhibitingaspecificphosphodiesterasetype5enzymewhichisfoundinvariousbodytissues,butprimarilyinthecorpuscavernosumpenis,aswellastheretina.Othersimilardrugsaresildenafil,tadalafilandvardenafil.TheadvantageofavanafilisthatithasveryfastonsetofactioncomparedwithotherPDE5inhibitors.Itisabsorbedquickly,reachingamaximumconcentrationinabout30–45minutes.Abouttwo-thirdsoftheparticipantswereabletoengageinsexualactivitywithin15minutes.