Pafuramidine Pafuramidine 5mg

CAS号：186953-56-0

品名：帕呋拉定N'-methoxy-4-[5-[4-[(Z)-N'-methoxycarbamimidoyl]phenyl]furan-2-yl]benzenecarboximidamide

中文别名：4,4'-(2,5-呋喃基)双[N-甲氧基苯甲脒];

英文别名：UNII-H1VG379J2X;Pafuramidine;

分子式：C20H20N4O3

分子量：364.398

精确质量：364.154

Psa：108.36

UNII号：H1VG379J2X

密度：1.25

熔点：192.5-193ºC

简介：Pafuramidine(formulatedasthemaleicacidsaltpafuramidinemaleate)isanexperimentaldrugforthetreatmentofpneumocystispneumonia(PCP).In2006,pafuramidinewasgivenorphandrugstatusbytheUSFoodandDrugAdministrationforPCPinpatientswithHIV/AIDS.Preliminaryclinicaltrialsindicatedthatpafuramidewaseffectiveagainstpneumocystispneumoniaandhadthepotentialforfewersideeffectsthanthestandardtreatmentwithtrimethoprim/sulfamethoxazole(TMP-SMX).