Torcetrapib Torcetrapi 1mg

CAS号：262352-17-0

品名：托彻普torcetrapib

中文别名：(2R,4S)-4-[(3,5-双三氟甲基苄基)甲氧基甲酰氨基]-2-乙基-6-三氟甲基-3,4-二氢-2H-喹啉-1-羧酸乙酯;

英文别名：Torcetrapib;ethyl(2R,4S)-4-[[3,5-bis(trifluoromethyl)phenyl]methyl-methoxycarbonylamino]-2-ethyl-6-(trifluoromethyl)-3,4-dihydro-2H-quinoline-1-carboxylate;

分子式：C26H22D3F9N2O4

分子量：603.492

精确质量：603.186

Psa：59.08

UNII号：4N4457MV2U

外观与性状：液体

密度：1.42g/cm3

沸点：504.8ºC at 760mmHg

熔点：54-58ºC

闪点：259.1ºC

折射率：1.511

蒸汽压：2.58E-10mmHg at 25°C

简介：Torcetrapib(CP-529,414,Pfizer)wasadrugbeingdevelopedtotreathypercholesterolemia(elevatedcholesterollevels)andpreventcardiovasculardisease.Itsdevelopmentwashaltedin2006whenphaseIIIstudiesshowedexcessiveall-causemortalityinthetreatmentgroupreceivingacombinationofatorvastatin(Lipitor)andtorcetrapib.