合成
CAS号：71-63-6
品名：洋地黄毒苷digitoxin
中文别名：洋地黄毒甙;
英文别名：tridigitoxosyldigitoxigenin;Ditaven;digicor;[3H]-Digitoxin;Natigal;Acedoxin;Myodigin;DIGITOXIN;Digimed;Digitrin;Cardigin;Card-20(22)-enolide,3-[(O-2,6-dideoxy-β-D-ribo-hexopyranosyl-(1-4)-O-2,6-dideoxy-β-D-ribo-hexopyranosyl-(1-4)-2,6-dideoxy-β-D,14-dihydroxy-;Digilong;De-Tone;
分子式：C41H64O13
分子量：764.939
精确质量：764.435
Psa：182.83
RTECS号：IH2275000
UNII号：E90NZP2L9U
外观与性状：白色粉末
密度：1.33 g/cm3
沸点：902.3ºC at 760 mmHg
熔点：240ºC (dec.)(lit.)
闪点：269.5ºC
折射率：1.593
储存条件：库房低温,通风,干燥,与食品原料分开存放
安全说明：S45
危险类别码：R23/25; R33
WGK Germany：3
危险品运输编码：UN 2811
危险类别：6.1(a)
包装等级：II
危险品标志：T
信号词：Danger
危险性防范说明：P261; P301 + P310; P311
危险标志：GHS06, GHS08
危险性描述：H301; H331; H373
简介：Digitoxinisacardiacglycoside.Itissimilarinstructureandeffectstodigoxin(thoughtheeffectsarelonger-lasting).Unlikedigoxin(whichiseliminatedfromthebodyviathekidneys),itiseliminatedviatheliver,socouldbeusedinpatientswithpoororerratickidneyfunction.However,itisnowrarelyusedincurrentWesternmedicalpractice.Whileseveralcontrolledtrialshaveshowndigoxintobeeffectiveinaproportionofpatientstreatedforheartfailure,theevidencebasefordigitoxinisnotasstrong,althoughitispresumedtobesimilarlyeffective.
用途：能加强心肌收缩力、减慢心率和抑制传导。适用于慢性心功能不全患者长期服用。
