耦合
CAS号：148893-10-1
品名：O-(7-氮杂苯并三唑-1-基)-N,N,N',N'-四甲基脲六氟磷酸盐2-(7-Aza-1H-Benzotriazole-1-yl)-1,1,3,3-TetramethyluroniumHexafluorophosphate
中文别名：HATU;2-(7-氮杂苯并三氮唑)-四甲基脲六氟磷酸盐;
英文别名：O-(7-Azabenzotriazol-1-yl)-N,N,N,N-tetramethyluroniumhexafluorophosphate;[dimethylamino(triazolo[4,5-b]pyridin-3-yloxy)methylidene]-dimethylazanium,hexafluorophosphate;2-(7-Aza-1H-benzotriazole-1-yl)-1,1,3,3-tetramethyluroniumhexafluorophosphate;O-(7-Azabenzotriazol-1-yl)-N,N,N',N'-tetramethyluroniumhexafluorophosphate;2-(7-Aza-1H-Benzotriazo;N,N,N',N'-Tetramethyl-O-(7-azabenzotriazol-1-yl)uroniumhexafluorophosphate;
分子式：C10H15F6N6OP
分子量：380.23
精确质量：380.095
Psa：72.67
MDL号：MFCD00274639
外观与性状：白色晶体粉末
密度：
沸点：176ºC at 760mmHg
熔点：183-188°C (dec.)
储存条件：2-8ºC
安全说明：S26-S37/39-S36/37
危险类别码：R36/37/38
WGK Germany：3
危险品标志：Xi
简介：HATU(1-[Bis(dimethylamino)methylene]-1H-1,2,3-triazolo[4,5-b]pyridinium3-oxidhexafluorophosphate)isareagentusedinpeptidecouplingchemistrytogenerateanactiveesterfromacarboxylicacid.HATUisusedalongwithHünig'sbase(N,N-diisopropylethylamine,DIPEA)toformamidebonds.GenerallyDMFisusedassolvent,althoughotherpolarorganicsolventscanalsobeused.
