抗生素
CAS号：120685-11-2
品名：米哚妥林midostaurin
中文别名：米哚妥林
英文别名：4'-N-benzoylstaurosprine;PKC412,[9S-(9α,10β,11β,13α)]-N-(2,3,10,11,12,13-Hexahydro-10-methoxy-9-methyl-1-oxo-9,13-epoxy-1H,9H-diindolo[1,2,3-gh:3',2',1'-lm]pyrrolo[3,4-j][1,7]benzodiazonin-11-yl)-N-methylbenzamide;Midostaurin;Benzoylstaurosporine;Cgp41251;4'-N-benzoylstaurosporine;
分子式：C35H30N4O4
分子量：570.637
精确质量：570.227
Psa：77.73
UNII号：ID912S5VON
密度：1.46g/cm3
折射率：1.76
储存条件：Store at 2-8ºC
危险品标志：T
简介：Midostaurin(PKC412)isamulti-targetproteinkinaseinhibitorbeinginvestigatedforthetreatmentofacutemyeloidleukemia(AML)andmyelodysplasticsyndrome(MDS).Itisasemi-syntheticderivativeofstaurosporine,analkaloidfromthebacteriumStreptomycesstaurosporeus,andisactiveinpatientswithmutationsofCD135(FMS-liketyrosinekinase3receptor,FLT3).
