氨基酸衍生物
CAS号：65391-42-6
品名：苯丁抑制素盐酸盐Bestatinhydrochloride
中文别名：N-[(2S,3R)-3-氨基-2-羟基-4-苯基丁酰基]-L-亮氨酸盐酸盐;盐酸乌苯美司;盐酸贝他定;贝他定盐酸;盐酸倍他定;N-[(2S,3R)-3-氨基-2-羟基-4苯基丁]-L-亮氨酸盐酸盐;
英文别名：BESTATINHYDROCHLORIDE;
分子式：C16H25ClN2O4
分子量：344.834
精确质量：344.15
Psa：112.65
EINECS号：613-790-2
密度：
沸点：604.7ºC at 760 mmHg
熔点：216-218°C
闪点：319.5ºC
储存条件：-20ºC
安全说明：S22; S24/25; S36; S26
危险类别码：R20/21/22
WGK Germany：3
海关编码：29242995
危险品标志：Xn
简介：Ubenimex(INN),alsoknownmorecommonlyasbestatin,isacompetitive,reversibleproteaseinhibitor.Itisaninhibitorofarginylaminopeptidase(aminopeptidaseB),leukotrieneA4hydrolase(azincmetalloproteasethatdisplaysbothepoxidehydrolaseandaminopeptidaseactivities),alanylaminopeptidase(aminopeptidaseM/N),leucyl/cystinylaminopeptidase(oxytocinase/vasopressinase),andmembranedipeptidase(leukotrieneD4hydrolase).Itisbeingstudiedforuseinthetreatmentofacutemyelocyticleukemia.ItisderivedfromStreptomycesolivoreticuli.Ubenimexhasbeenfoundtoinhibittheenzymaticdegradationofoxytocin,vasopressin,enkephalins,andvariousotherpeptidesandcompounds.
