合成
CAS号：67-99-2
品名：胶霉素gliotoxin
中文别名：胶黏毒素;
英文别名：Gliotoxin,(3R,5aS,6S,10aR)-2,3,5a,6-Tetrahydro-6-hydroxy-3-(hydroxymethyl)-2-methyl-10H-3,10a-epidithiopyrazino[1,2-a]indole-1,4-dione;
分子式：C13H14N2O4S2
分子量：326.391
精确质量：326.039
Psa：131.68
RTECS号：KB4725000
UNII号：5L648PH06K
密度：1.74g/cm3
沸点：699.7ºC at 760 mmHg
熔点：153.5ºC
闪点：377ºC
折射率：1.813
储存条件：库房通风低温干燥,与食品原料分开储运
危险类别码：R25
WGK Germany：3
危险品运输编码：UN 3462 6.1/PG 3
危险类别：6.1(b)
包装等级：III
简介：Gliotoxinisasulfur-containingmycotoxinthatbelongstoaclassofnaturallyoccurring2,5-diketopiperazinesproducedbyseveralspeciesoffungi,especiallythoseofmarineorigin.Itisthemostprominentmemberoftheepipolythiopiperazines,alargeclassofnaturalproductsfeaturingadiketopiperazinewithdi-orpolysulfidelinkage.Thesehighlybioactivecompoundshavebeenthesubjectofnumerousstudiesaimedatnewtherapeutics.GliotoxinwasoriginallyisolatedfromGliocladiumfimbriatum,andwasnamedaccordingly.Itisanepipolythiodioxopiperazinemetabolite.
用途：具有免疫调节活性,抗菌谱较广,能抑制霉菌、细菌和病毒,也可用作农药。
