合成
CAS号:82-02-0
品名:凯林4,9-dimethoxy-7-methylfuro[3,2-g]chromen-5-one
中文别名:呋喃并色酮;
英文别名:5H-Furo[3,2-g][1]benzopyran-5-one,4,9-dimethoxy-7-methyl-;5,8-dimethoxy-2-methyl-4',5'-furo-6,7-chromane;Kelourin;Methafrone;Corafurone;Ammivisnagen;Ammispasmin;khellin;Amicardine;Coronin;Rykellin;Visammin;
分子式:C14H12O5
分子量:260.242
精确质量:260.068
Psa:61.81
EINECS号:201-392-8
MDL号:MFCD00005007
外观与性状:淡黄色结晶
密度:1.301 g/cm3
沸点:482.1ºC at 760 mmHg
熔点:150-154ºC
闪点:218.8ºC
折射率:1.595
储存条件:库房通风低温干燥
安全说明:36/37/39-45
危险类别码:R25
海关编码:2932999099
危险品运输编码:UN 2811 6.1/PG 3
危险类别:6.1(b)
包装等级:III
危险品标志:T
简介:Khellinhasbeenusedasanherbalfolkmedicine,withuseintheMediterraneandatingbacktoAncientEgypt,totreatavarietyofmaladiesincluding:renalcolic,kidneystones,coronarydisease,bronchialasthma,vitiligo,andpsoriasis.ItisamajorconstituentoftheplantAmmivisnaga,alsoknownasBishop'sWeed.Oncepurified,khellinexistsascolorless,odorless,bitter-tastingneedle-shapedcrystalsandisclassifiedasagamma-pyrone,afuranochromonederivative.Intheearly20thcentury,researcherssearchedforkhellinanalogswithlowertoxicityandbetterefficacy.Anumberofdrugswerediscoveredthroughthisresearch,suchasamiodaroneandcromolynsodium,whichareusedincurrentmedicalpractice.
用途:生化研究。医用血管舒张剂。