科立内脂二醇 (-)-Coreylactonediol 2500mg

CAS号：32233-40-2

品名：(-)-6beta-羟甲基-7alpha-羟基-顺式-2-氧杂双环[3.3.0]辛-3-酮(3aR,4S,5R,6aS)-5-hydroxy-4-(hydroxymethyl)-3,3a,4,5,6,6a-hexahydrocyclopenta[b]furan-2-one

中文别名：科立内脂二醇;Corey二醇;(-)-科立内酯;(3aR,4S,5R,6aS)-(-)-四氢-5-羟基-4-(羟甲基)-2H-环戊[b]呋喃-2-酮;(-)-科里内酯;(3aR,4S,5R,6aS)-(-)-六氢-5-羟基-4-(羟甲基)-2H-环戊并[b]呋喃-2-酮;

英文别名：(3aR,4S,5R,6aS)-5-Hydroxy-4-(hydroxymethyl)hexahydro-2H-cyclopenta[b]furan-2-one;(3aR,4S,5R,6aS)-(-)-Hexahydro-5-hydroxy-4-(hydroxymethyl)-2H-cyclopenta[b]furan-2-one;(-)-Coreylactone;(-)-CoreyLactoneDiol;(-)-6beta-Hydroxymethyl-7alpha-hydroxy-cis-2-oxabicyclo[3.3.0]octan-3-one;

分子式：C8H12O4

分子量：172.178

精确质量：172.074

Psa：66.76

EINECS号：608-721-8

外观与性状：白色至米色-棕色结晶粉末或晶体

密度：1.365 g/cm3

沸点：406.6ºC at 760 mmHg

熔点：117-119°C(lit.)

闪点：172.9ºC

折射率：1.545

储存条件：-20ºC

安全说明：S24/25

危险类别码：R24/25

WGK Germany：3

海关编码：2932209090

简介：(-)-CoreyLactoneDiolisanintermediateofIloprostandshowsinhibitoryactivitytowardsβ-lactamase.IloprostisasyntheticanalogueofProstacyclin(PGI2)usedtotreatpulmonaryarterialhypertension(PAH),scleroderma,Raynaud'sphenomenonandischemia.