CAS:565460-15-3
565460-15-3
CAS号：565460-15-3
品名：3-(环已氧羰基胺基)联苯cyclohexylN-(3-phenylphenyl)carbamate
中文别名：[1,1-联苯]-3-氨基甲酸环己酯;
英文别名：N-Biphenyl-3-ylcarbamicacid,cyclohexylester;MonoacylglycerolLipaseInhibitor,URB602;Biphenyl-3-ylCarbamicAcid,CyclohexylEster;cyclohexylester;URB602;cyclohexylbiphenyl-3-ylcarbamate;
分子式：C19H21NO2
分子量：295.376
精确质量：295.157
Psa：38.33
MDL号：MFCD08457914
外观与性状：灰白色固体
密度：1.149g/cm3
沸点：416.611ºC at 760 mmHg
熔点：122-123ºC
闪点：205.759ºC
折射率：1.595
海关编码：2924299090
简介：URB602([1,1'-biphenyl]-3-yl-carbamicacid,cyclohexylester)isacompoundthathasbeenfoundtoinhibithydrolysisofmonoacylglycerolcompounds,suchas2-arachidonoylglycerol(2-AG)and2-oleoylglycerol(2-OG).Itwasfirstdescribedin2003.Astudyperformedin2005foundthatthecompoundhadspecificityformetabolizing2-AGoveranandamide(anothercannabinoidligand)inratbrainpresumablybyinhibitingtheenzymemonoacylglycerollipase(MAGL),whichistheprimarymetabolicenzymeof2-AG.However,subsequentstudieshaveshownthatURB602lacksspecificityforMAGLinhibitioninvitro.
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