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CAS:382180-17-8
382180-17-8
CAS号：382180-17-8
品名：N-羟基-N'-3-吡啶基辛二酰胺N'-hydroxy-N-pyridin-3-yloctanediamide
中文别名：N-羟基-N'-3-吡啶基辛烷二酰胺;
英文别名：pyroxamide;N1-Hydroxy-N8-3-pyridinyl-octanediamide;N-Hydroxy-N'-3-pyridinyloctanediamide;
分子式：C13H19N3O3
分子量：265.308
精确质量：265.143
Psa：91.32
MDL号：MFCD13194970
密度：1.215 g/cm3
折射率：1.569
海关编码：2933399090
信号词：Warning
危险标志：GHS07
危险性描述：H302
简介：Pyroamideisahistonedecetylaseinhibitor(HDCi),anovelclassofanti-neoplasticagentthatactsbyenhancingacetylationofhistones,promotinguncoilingofchromatinandactivationofgenesimplicatedintheregulationofcellsurvivalsuchaspoliferation,differentiationandapoptosis.PyroamideisknowntopotentlyinhibitsaffinitypurifiedHDAC1.Alsoinhibitsthegrowthoftumorcellsinvitroandinvivo.Inducesp21/WAF1expressionintumorcells.
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