CAS号:104206-65-7
品名:尼替西农nitisinone
中文别名:2-(2-硝基-4-三氟甲基苯甲酰基)-1,3-环己二酮;
英文别名:Nitisinone;2-[2-nitro-4-(trifluoromethyl)benzoyl]cyclohexane-1,3-dione;Nitisone;2-(2-nitro-4-(trifluoromethyl)benzoyl)cyclohexane-1,3-dione;Orfadin;Nitisinone[INN];nitisinona;Orfadin(TN);nitisinonum;
分子式:C14H10F3NO5
分子量:329.228
精确质量:329.051
Psa:97.03
MDL号:MFCD01752192
密度:1.484g/cm3
沸点:486.2ºC at 760mmHg
闪点:247.9ºC
折射率:1.535
蒸汽压:1.32E-09mmHg at 25°C
海关编码:2914700090
简介:Nitisinone(INN),alsoknownasNTBC(anabbreviationofitsfullchemicalname)isamedicationusedtoslowtheeffectsofhereditarytyrosinemiatype1.Sinceitsfirstuseforthisindicationin1991,ithasreplacedlivertransplantationasthefirst-linetreatmentforthisrarecondition.Itisalsobeingstudiedintherelatedconditionalkaptonuria.ItismarketedunderthebrandnameOrfadinbythecompanySwedishOrphanBiovitrum(Sobi);itwasfirstbroughttomarketbySwedishOrphanInternational.Itwasoriginallydevelopedasacandidateherbicide.
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