CAS:102146-07-6
102146-07-6
CAS号：102146-07-6
品名：8-环戊烷基-1,3-二丙基黄嘌呤8-Cyclopentyl-1,3-dipropylxanthine
中文别名：1,3-二丙基-8-环戊基黄嘌呤;8-环戊-1,3-二丙基黄嘌呤;
英文别名：8-cyclopentyl-1,3-dipropyl-7H-purine-2,6-dione;8-Cyclopentyl-1,3-dipropyl-1H-purine-2,6(3H,7H)-dione;
分子式：C16H24N4O2
分子量：304.387
精确质量：304.19
Psa：72.68
MDL号：MFCD00055117
PubChem号：24277697
密度：1.195g/cm3
沸点：535.1ºC at 760mmHg
熔点：178°C
闪点：277.4ºC
折射率：1.564
蒸汽压：1.59E-11mmHg at 25°C
安全说明：S26-S36
危险类别码：R36/37/38
WGK Germany：3
海关编码：2933990090
危险品标志：Xi
信号词：Warning
危险性防范说明：P261; P305 + P351 + P338
危险标志：GHS07
危险性描述：H315; H319; H335
简介：8-Cyclopentyl-1,3-dipropylxanthine(DPCPX,PD-116,948)isadrugwhichactsasapotentandselectiveantagonistfortheadenosineA1receptor.IthashighselectivityforA1overotheradenosinereceptorsubtypes,butaswithotherxanthinederivativesDPCPXalsoactsasaphosphodiesteraseinhibitor,andisalmostaspotentasrolipramatinhibitingPDE4.IthasbeenusedtostudythefunctionoftheadenosineA1receptorinanimals,whichhasbeenfoundtobeinvolvedinseveralimportantfunctionssuchasregulationofbreathingandactivityinvariousregionsofthebrain,andDPCPXhasalsobeenshowntoproducebehaviouraleffectssuchasincreasingthehallucinogen-appropriaterespondingproducedbythe5-HT2AagonistDOI,andthedopaminereleaseinducedbyMDMA,aswellashavinginteractionswitharangeofanticonvulsantdrugs.
合成
