CAS:63547-13-7
63547-13-7
CAS号：63547-13-7
品名：艾捉非尼Adrafinil
中文别名：N-羟基二苯甲基亚硫酰基乙酰胺;二苯甲基亚硫酰基乙酰羟胺;阿屈非尼;
英文别名：2-[(Diphenylmethyl)sulfinyl]acetohydroxamicacid;benzhydrylsulphinyl-acetohydroxamicacid;[2-(diphenyl)methanesulfinyl]-N-hydroxy-acetamide;2-(Benzhydrylsulfinyl)acetohydroxamicacid;2-(benzhydrylsulphinyl)acetohydroxamicacid;Olmifon;Acetamide,2-((diphenylmethyl)sulfinyl)-N-hydroxy;2-benzhydrylsulfinyl-N-hydroxyacetamide;
分子式：C15H15NO3S
分子量：289.35
精确质量：289.077
Psa：85.61
RTECS号：AB8139500
MDL号：MFCD00865357
外观与性状：白色,吸湿的粉末
密度：1.342 g/cm3
熔点：159-1600C
折射率：1.652
稳定性：Stable at normal temperatures and pressures.
储存条件：Keep tightly closed.
危险类别码：R22
WGK Germany：3
海关编码：2942000000
危险品标志：Xn
简介：Adrafinil(INN)(brandnameOlmifon)isadiscontinuedwakefulness-promotingagent(oreugeroic)thatwasformerlyusedinFrancetopromotevigilance(alertness),attention,wakefulness,mood,andotherparameters,particularlyintheelderly.Itwasalsousedoff-labelbyindividualswhowishedtoavoidfatigue,suchasnightworkersorotherswhoneededtostayawakeandalertforlongperiodsoftime.Additionally,\"adrafinilisknowntoalargernonscientificaudience,whereitisconsideredtobeanootropicagent.\";Adrafinilisaprodrug;itisprimarilymetabolizedinvivotomodafinil,resultinginverysimilarpharmacologicaleffects.Unlikemodafinil,however,ittakestimeforthemetabolitetoaccumulatetoactivelevelsinthebloodstream.Effectsusuallyareapparentwithin45–60minuteswhentakenorallyonanemptystomach.
用途：非苯丙胺类精神兴奋药，其作用是苏醒和提高警觉性。用于老年人觉醒障碍和抑郁症状的对症治疗。
合成
