CAS:149888-94-8
149888-94-8
CAS号：149888-94-8
品名：盐酸阿齐利特1-[(E)-[5-(4-chlorophenyl)furan-2-yl]methylideneamino]-3-[4-(4-methylpiperazin-1-yl)butyl]imidazolidine-2,4-dione,dihydrochloride
中文别名：盐酸阿齐利特
英文别名：azmilide;Azimilidehydrochloride;Stedicor;AzimilideHCl;Azimilidedihydrochloride;
分子式：C23H30Cl3N5O3
分子量：530.875
精确质量：529.141
Psa：72.6
密度：1.32g/cm3
沸点：594.9ºC at 760mmHg
闪点：313.6ºC
简介：AzimilideDihydrochlorideisanoraltypeIIIpotassiumchannelblockeragentthatblocksboththerapidactivatingcomponentandtheslowactivatingcomponentofthedelayedrectifierpotassiumcurrent.Bothpreclinicalandclinicalstudieshavedemonstratedtheefficacyofazimilideanditssafetyinthetreatmentofsupraventricularandventriculartachyarrhythmia.Azimilidealsoisbeingstudiedinaworldwidemulticentertrialforpreventionofsuddencardiacdeathinpatientsaftermyocardialinfarction.
合成
