CAS:58-46-8
58-46-8
CAS号：58-46-8
品名：丁苯那嗪9,10-dimethoxy-3-isobutyl-1,3,4,6,7,11b-hexahydro-2H-pyrido[2,1-a]isoquinolin-2-one
中文别名：丁苯喹嗪;顺式-9,10-二甲氧基-1,3,4,6,7,11B-六氢-3-异丁基-2H-苯并[A]喹嗪-2-酮;3-异丁基-9,10-二甲氧基-1,3,4,6,7,11b-六氢-2H-苯并[a]喹啉-2-酮;
英文别名：2H-Benzo[a]quinolizin-2-one,1,3,4,6,7,11b-hexahydro-9,10-dimethoxy-3-(2-methylpropyl)-;TETRABENAZINE;Tetrabenazine,(3R,11bR)-rel-1,3,4,6,7,11b-hexahydro-9,10-dimethoxy-3-(2-methylpropyl)-2H-benzo[a]quinolizin-2-one;Nitoman;Rubigen;Ro1-9569;
分子式：C19H27NO3
分子量：317.423
精确质量：317.199
Psa：38.77
UNII号：Z9O08YRN8O
密度：1.12
沸点：448.9ºC at 760mmHg
熔点：128-130ºC
闪点：225.3ºC
折射率：1.554
储存条件：2-8ºC
危险类别码：R22
海关编码：2933990090
危险品运输编码：UN 3249
危险类别：6.1(b)
包装等级：III
危险品标志：Xn
信号词：Warning
危险标志：GHS07
危险性描述：H302
简介：Tetrabenazineisadrugforthesymptomatictreatmentofhyperkineticmovementdisorders.ItismarketedunderthetradenamesNitomaninCanadaandXenazineinNewZealandandsomepartsofEurope,andisavailableasXenazineintheUnitedStatesasanorphandrug.OnAugust15,2008,theU.S.FoodandDrugAdministrationapprovedtheuseoftetrabenazinetotreatchoreaassociatedwithHuntington'sdisease.Althoughotherdrugshadbeenused\"offlabel,\"tetrabenazinewasthefirstapprovedtreatmentforHuntington'sdiseaseintheU.S.Thecompoundhasbeenknownsincethe1950s.
合成
