CAS:1428-67-7
1428-67-7
CAS号：1428-67-7
品名：2,3-双(4-羟苯基)丙腈2,3-bis(4-hydroxyphenyl)propionitrile
中文别名：2,3-双(4-羟苯基)丙腈
英文别名：2,3-bis(4-hydroxyphenyl)propanenitrile;2,3-Bis(4-hydroxyphenyl)propionitrile;DPNDiarylpropionitrileSC-4473;
分子式：C15H13NO2
分子量：239.269
精确质量：239.095
Psa：64.25
外观与性状：灰白色固体
密度：1.256 g/cm3
沸点：449.4ºC at 760 mmHg
闪点：225.6ºC
折射率：1.639
蒸汽压：1.08E-08mmHg at 25°C
信号词：Warning
危险性防范说明：P273; P305 + P351 + P338
危险标志：GHS07, GHS09
危险性描述：H319; H400
简介：Diarylpropionitrile(DPN),alsoknownas2,3-bis(p-hydroxyphenyl)propionitrile(2,3-BHPPN),isasynthetic,non-steroidal,andhighlyselectiveagonistofERβ(IC50=15nM)thatisusedwidelyinscientificresearchtostudythefunctionofthisreceptor.Itis70-foldmoreselectiveforERβoverERα,andhas100-foldloweraffinityforGPER(GPR30)relativetoestradiol.DPNproducesantidepressant-andanxiolytic-likeeffectsinanimalsviaactivationoftheendogenousoxytocinsystem.
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