CAS:781649-09-0
781649-09-0
CAS号：781649-09-0
品名：N-[(3R,6S)-6-(2,3-二氟苯基)六氢-2-氧代-1-(2,2,2-三氟乙基)-1H-氮杂卓-3-基]-4-(2,3-二氢-2-氧代-1H-咪唑并[4,5-b]吡啶-1-基)-1-哌啶甲酰胺N-[(3R,6S)-6-(2,3-difluorophenyl)-2-oxo-1-(2,2,2-trifluoroethyl)azepan-3-yl]-4-(2-oxo-3H-imidazo[4,5-b]pyridin-1-yl)piperidine-1-carboxamide
中文别名：N-[(3R,6S)-6-(2,3-二氟苯基)六氢-2-氧代-1-(2,2,2-三氟乙基)-1H-氮杂卓-3-基]-4-(2,3-二氢-2-氧代-1H-咪唑并[4,5-b]吡啶-1-基)-1-哌啶甲酰胺
英文别名：Telcagepant;MK0974;
分子式：C26H27F5N6O3
分子量：566.523
精确质量：566.206
Psa：103.33
UNII号：D42O649ALL
密度：1.54
简介：Telcagepant(INN)(codenameMK-0974)isacalcitoningene-relatedpeptidereceptorantagonistwhichwasaninvestigationaldrugfortheacutetreatmentandpreventionofmigraine,developedbyMerck&Co.Intheacutetreatmentofmigraine,itwasfoundtohaveequalpotencytorizatriptanandzolmitriptanintwoPhaseIIIclinicaltrials.Thecompanyhasnowterminateddevelopmentofthedrug.
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