CAS:874902-19-9
874902-19-9
CAS号：874902-19-9
品名：5-([1,1’-联苯]-4-甲基)-N,N-二甲基-1H-四氮唑-1-甲酰胺N,N-dimethyl-5-[(4-phenylphenyl)methyl]tetrazole-1-carboxamide
中文别名：5-([1,1'-联苯]-4-甲基)-N,N-二甲基-1H-四氮唑-1-甲酰胺;
英文别名：HMS3269E15;1H-Tetrazole-1-carboxamide;
分子式：C17H17N5O
分子量：307.35
精确质量：307.143
Psa：63.91
UNII号：2WBU91OKM7
密度：1.22g/cm3
沸点：506.103ºC at 760 mmHg
熔点：87-88ºC
闪点：259.882ºC
折射率：1.64
储存条件：Store at +4ºC
危险类别码：R22
简介：LY-2183240isadrugwhichactsbothasapotentinhibitorofthereuptakeoftheendocannabinoidanandamideandasaninhibitoroffattyacidamidehydrolase(FAAH),theprimaryenzymeresponsiblefordegradinganandamide.Thisleadstomarkedlyelevatedanandamidelevelsinthebrain,andLY-2183240hasbeenshowntoproducebothanalgesicandanxiolyticeffectsinanimalmodels.WhileLY-2183240isapotentinhibitorofFAAH,ithasrelativelypoorselectivityandalsoinhibitsseveralotherenzymesidetargets.Consequently,itwasneverdevelopedforclinicaluse,thoughitremainswidelyusedinresearch,andhasalsobeensoldasadesignerdrug.
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