CAS:64887-14-5
64887-14-5
CAS号：64887-14-5
品名：盐酸乌拉地尔UrapidilHydrochloride
中文别名：盐酸乌拉地尔
英文别名：6-[3-[4-(2-methoxyphenyl)piperazin-1-yl]propylamino]-1,3-dimethylpyrimidine-2,4-dione,hydrochloride;
分子式：C20H30ClN5O3
分子量：423.937
精确质量：423.204
Psa：71.74
RTECS号：YQ9862000
UNII号：PVU92PZO12
外观与性状：白色或灰白色结晶粉末
密度：
沸点：549ºC at 760 mmHg
熔点：156-158ºC
闪点：285.8ºC
储存条件：Desiccate at RT
安全说明：S36
危险类别码：R22
WGK Germany：3
海关编码：3004909090
危险品标志：Xn
简介：Urapidilisasympatholyticantihypertensivedrug.Itactsasanα1-adrenoceptorantagonistandasan5-HT1AreceptoragonistAlthoughaninitialreportsuggestedthaturapidilwasalsoanα2-adrenoceptoragonist,thiswasnotsubstantiatedinlaterstudiesthatdemonstrateditwasdevoidofagonistactionsinthedogsaphenousveinandtheguinea-pigileum.Unlikesomeotherα1-adrenoceptorantagonists,urapidildoesnotelicitreflextachycardia,andthismayberelatedtoitsweakβ1-adrenoceptorantagonistactivity,aswellasitseffectoncardiacvagaldrive.UrapidiliscurrentlynotapprovedbytheU.S.FoodandDrugAdministration,butitisavailableinEurope.
神经信号
