CAS:566-48-3
566-48-3
CAS号：566-48-3
品名：福美司坦formestane
中文别名：4-雄烯-4-醇-3,17-二酮;福美斯坦;4-羟基雄甾烷-4-烯-3,17-二酮;
英文别名：Lentaron;(8R,9S,10R,13S,14S)-4-hydroxy-10,13-dimethyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthrene-3,17-dione;B,Aromataseinhibitor;4-Hydroxyandrost-4-ene-3,17-dione;4-Hydroxy-4-androstene-3,17-dione;4-androsten-4-ol-3,17-dione;4-Hydroxyandrostenedione;4-OH-A;Formestane;
分子式：C19H26O3
分子量：302.408
精确质量：302.188
Psa：54.37
RTECS号：BV8152500
UNII号：PUB9T8T355
外观与性状：白色粉末
密度：1.19g/cm3
沸点：475.4ºC at 760mmHg
熔点：199-202°C
闪点：255.4ºC
折射率：1.545
储存条件：2-8ºC
安全说明：S53-S36/37/39-S45
危险类别码：R60
WGK Germany：3
危险品标志：T
简介：Formestane(tradenameLentaron)isatypeI,steroidal,selectivearomataseinhibitor.Itisusedinthetreatmentofestrogenreceptor-positivebreastcancerinpostmenopausalwomen.Thedrugisnotactiveorally,andisinsteadavailableonlyasanintramusculardepotinjection.Becauseofthis,itisnolongerpopularasmanyorallyactivearomataseinhibitorshavebeenidentifiedandintroduced.Formestaneisananalogueofandrostenedione.
用途：1.芳香化酶抑制剂。用于进行性乳腺癌。
酶抑制剂
