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CAS:186953-56-0
186953-56-0
CAS号：186953-56-0
品名：帕呋拉定N'-methoxy-4-[5-[4-[(Z)-N'-methoxycarbamimidoyl]phenyl]furan-2-yl]benzenecarboximidamide
中文别名：4,4'-(2,5-呋喃基)双[N-甲氧基苯甲脒];
英文别名：UNII-H1VG379J2X;Pafuramidine;
分子式：C20H20N4O3
分子量：364.398
精确质量：364.154
Psa：108.36
UNII号：H1VG379J2X
密度：1.25
熔点：192.5-193ºC
简介：Pafuramidine(formulatedasthemaleicacidsaltpafuramidinemaleate)isanexperimentaldrugforthetreatmentofpneumocystispneumonia(PCP).In2006,pafuramidinewasgivenorphandrugstatusbytheUSFoodandDrugAdministrationforPCPinpatientswithHIV/AIDS.Preliminaryclinicaltrialsindicatedthatpafuramidewaseffectiveagainstpneumocystispneumoniaandhadthepotentialforfewersideeffectsthanthestandardtreatmentwithtrimethoprim/sulfamethoxazole(TMP-SMX).
微生物Microbiology
