CAS:376348-65-1
376348-65-1
CAS号：376348-65-1
品名：马拉韦罗Maraviroc
中文别名：马拉韦罗;马拉韦若;4,4-二氟-N-[(1S)-3-[(1R,5S)-3-(3-甲基-5-异丙基-1,2,4-三唑-4-基)-8-氮杂双环[3.2.1]辛烷-8-基]-1-苯基丙基]环己烷-1-甲酰胺;
英文别名：Selzentry;Celsentri;maroviroc;4,4-Difluoro-N-[(1S)-3-{(1R,3s,5S)-3-[3-methyl-5-(propan-2-yl)-4H-1,2,4-triazol-4-yl]-8-azabicyclo[3.2.1]octan-8-yl}-1-phenylpropyl]cyclohexanecarboxamide;4,4-difluoro-N-((S)-3-((1R,3S,5S)-3-(3-isopropyl-5-methyl-4H-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octan-8-yl)-1-phenylpropyl)cyclohexane-1-carboxamide;4,4-Difluoro-N-[(1S)-3-[(3-exo)-3-[3-methyl-5-(1-methylethyl-d6)-4H-1,2,4-triazol-4-yl]-8-azabicyclo[3.2.1]oct-8-yl]-1-phenylpropyl]cyclohexanecarboxamide;UK427857;
分子式：C29H41F2N5O
分子量：513.666
精确质量：513.328
Psa：63.05
UNII号：MD6P741W8A
外观与性状：棕色固体
密度：1.29 g/cm3
熔点：79-81ºC
折射率：1.627
海关编码：2934999090
简介：Maraviroc(brand-namedSelzentry,orCelsentrioutsidetheU.S.)isanantiretroviraldrugintheCCR5receptorantagonistclassusedinthetreatmentofHIVinfection.Itisalsoclassedasanentryinhibitor.Italsoappearedtoreducegraft-versus-hostdiseaseinpatientstreatedwithallogeneicbonemarrowtransplantationforleukemia,inaphase1/2study.
微生物Microbiology
